ISSYS Awarded Patent for Implantable Medical Sensors

YPSILANTI, MI /Marketwire/ -- Integrated Sensing Systems, Inc. (ISSYS) announced that the U.S. Patent Office has granted a patent titled "System for monitoring conduit obstruction" (U.S. Patent No. 7,211,048), which covers the design and manufacturing of a wireless implantable sensing system for noninvasive monitoring of pressure and/or pressure gradients in a cardiac conduit.

Certain heart defects require implantation of a cardiac blood-flow conduit to bypass valve aplasia or severe stenosis. One of the main issues with implanted cardiac conduits is that over time calcification or stenosis will occur, and in nearly all cases, occlusion will occur eventually. ISSYS' novel implantable wireless sensing system allows physicians a means for accurate and noninvasive monitoring of conduit condition on a continuous basis. Using the data provided by ISSYS' sensors, physicians can continuously monitor both pressure and blood flow rate within the conduit to determine whether and when conduit revision is required. Furthermore, remote monitoring of conduit condition would simultaneously reduce the number of hospital and clinic visits while increasing the overall timeliness of treatment.

Dr. Nader Najafi, ISSYS CEO, stated that "ISSYS has already established a solid patent portfolio to cover the design and technology of its wireless implant platform. It is exciting to see that the recently awarded patents are now covering the medical applications of our technology." ISSYS technology supports the trend toward home health monitoring and has the potential to revolutionize the way many diseases are treated. The particular targets of ISSYS products are cardiovascular disease, especially congestive heart failure, hydrocephalus (high brain pressure), and traumatic brain injuries.

Company Background
ISSYS is a leader in advanced micromachining technologies for medical devices and microfluidic and scientific analytical sensing applications. Founded in 1995, ISSYS is one of the oldest independent MEMS companies in the U.S. ISSYS operates a "full manufacturing under one roof," multi-million-dollar, state-of-the-art MEMS fabrication facility near Ann Arbor, MI. An ISO 9001:2000 certified organization and ISO 13485 qualified, ISSYS is a vertically integrated company dedicated to developing and manufacturing system-level products based on MEMS technology (MEMS Inside). For more company, product, and service information, please visit our Web site.

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