FES devices restore movement to paralyzed arms and legs. They send electrical impulses to electrodes—implanted in the body, worn on the skin, or operating through the skin—to produce and control movement. Adapting the FES device for each patient was a time-consuming process, as the device software needed multiple iterations for a customized response to each patient's needs.
The Cleveland FES Center, at Case Western Reserve University, developed the Universal External Control Unit (UECU) to address the need for tailored FES devices. With the UECU's modular software and hardware design, research engineers in the clinic can modify a FES controller application and immediately test the results.
With MathWorks tools, teams are able to develop, test, and implement algorithms that suit specific patient scenarios, reducing the traditional development cycle for some FES functions to less than a day.
"All of our FES applications used to be built by dedicated programmers using C code," said Robert Kirsch, PhD, Professor, Biomedical Engineering, Case Western Reserve University and Associate Director of Technology, Cleveland FES Center. "The overall process was slow because everything had to be done by our central programmers, which limited how quickly we could move from idea to implementation. MathWorks tools for model-based design provide the flexibility and ease of use that enables our clinical groups to develop and refine FES applications on their own."
"An approach like model-based design is ideal for researchers and scientists who may not have an extensive software programming background but who are still involved in product design and development," said Paul Barnard, marketing director - design automation, at The MathWorks. "The creation of industry firsts, such as the UECU, demonstrates just how critical MathWorks tools have become in the field of biomedical research."
The UECU project involved a range of MathWorks products beyond MATLAB and Simulink, including Signal Processing Blockset, Stateflow, Real-Time Workshop, xPC Target, and xPC Target Embedded Option. More than 30 UECUs are currently in use by patients today, and over the next decade, the Cleveland FES Center aims to introduce a new technology that is a fully internal system, inside the body. This modular and expandable system is expected to provide patients with more functionality and independence. The lab prototypes of the new system are already running programs created with Simulink and Real-Time Workshop.
About Cleveland FES Center
The Cleveland FES Center is a consortium of three nationally recognized institutions: the Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, and MetroHealth Medical Center. The Cleveland FES Center is dedicated to the advancement and clinical deployment of technologies that generate or suppress activity in the nervous system; including technology that produces and controls the movement of otherwise paralyzed limbs.
About The MathWorks
The MathWorks is the leading developer of mathematical computing software. MATLAB, the language of technical computing, is a programming environment for algorithm development, data analysis, visualization, and numeric computation. Simulink is a graphical environment for simulation and Model-Based Design of multidomain dynamic and embedded systems. Engineers and scientists worldwide rely on these product families to accelerate the pace of discovery, innovation, and development in automotive, aerospace, electronics, financial services, biotech-pharmaceutical, and other industries.
MathWorks products are also fundamental teaching and research tools in the world's universities and learning institutions. Founded in 1984, The MathWorks employs more than 2,100 people in 15 countries, with headquarters in Natick, MA, USA.
About Case Western Reserve University
Case Western Reserve University is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case Western Reserve is distinguished by its strengths in education, research, service, and experiential learning. Located in Cleveland, Case Western Reserve offers nationally recognized programs in the arts and sciences, dental medicine, engineering, law, management, medicine, nursing, and social work.